La ricerca nell’ambito delle neuroscienze ha permesso di raggiungere livelli di diagnosi e di cure fino a poco tempo fa impensabili. Per migliorare la qualità della vita delle persone ed arrivare ad una medicina di precisione anche in ambito neurospichiatrico, siamo convinti che clinica e ricerca debbano sempre camminare insieme. Con questa convinzione e con questo obiettivo, il Brain Center Firenze svolge attività di ricerca nell’ambito delle neuroscienze applicata alla cura dei disturbi neuropsichiatrici.
La nostra attività di ricerca si avvale di collaborazioni nazionali e internazionali e si articola attraverso la pubblicazione di lavori su riviste internazionali peer-reviewed, la loro divulgazione a congressi, la partecipazione a gruppi di ricerca, il lavoro editoriale in riviste scientifiche internazionali. Tutte le ricerche condotte al Brain Center Firenze sono approvate dal comitato etico competente.
Qui di seguito le più recenti pubblicazioni:
How does “Pure-O” obsessive-compulsive disorder impact on a patient’s treatment plan?
Who really hoards? Hoarding symptoms in adults with attention-deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD) and healthy controls
Will Transcranial Magnetic Stimulation Improve the Treatment of Obsessive–Compulsive Disorder?
Treatment-resistant OCD: Pharmacotherapies in adults
Nuova pubblicazione sulla rivista Comprehensive Psychiatry della Elsevier
Obsessive-compulsive disorder during the COVID-19 pandemic
Impulsività, Processi Decisionali e Sistema della Ricompensa come fattori chiave nelle dipendenze
Nuova pubblicazione sulla rivista internazionale CNS Spectrum della Cambridge University Press
Nuova pubblicazione sul trattamento dei comportamenti impulsivi e compulsivi nel Parkinson sulla rivista internazionale Neurological Science
Nuovo studio pubblicato sulla rivista internazionale CNS Spectrum della Cambridge Press
Pubblicato nuovo articolo sulla rivista internazionale “Journal of Experimental Pharmacology”
How to manage obsessive-compulsive disorder (OCD) under COVID-19
Qui di seguito tutte le pubblicazioni:
Articoli su riviste internazionali peer-reviewed:
Grassi G, Cecchelli C, Mazzocato G, Vignozzi L. Early onset obsessive-compulsive disorder: the biological and clinical phenotype. CNS Spectr. 2021 Feb 1:1-7.
Grassi G, Cecchelli C, Vignozzi L, Pacini S. Investigational and Experimental Drugs to Treat Obsessive-Compulsive Disorder. J Exp Pharmacol. 2021 Jan 5;12:695-706.
Fineberg NA, Van Ameringen M, Drummond L, Hollander E, Stein DJ, Geller D, Walitza S, Pallanti S, Pellegrini L, Zohar J, Rodriguez CI, Menchon JM, Morgado P, Mpavaenda D, Fontenelle LF, Feusner JD, Grassi G, Lochner C, Veltman DJ, Sireau N, Carmi L, Adam D, Nicolini H, Dell’Osso B. How to manage obsessive-compulsive disorder (OCD) under COVID-19: A clinician’s guide from the International College of Obsessive Compulsive Spectrum Disorders (ICOCS) and the Obsessive-Compulsive and Related Disorders Research Network (OCRN) of the European College of Neuropsychopharmacology. Compr Psychiatry. 2020 Jul;100:152174.
Benatti B, Ferrari S, Grancini B, Girone N, Briguglio M, Marazziti D, Mucci F, Dell’Osso L, Gambini O, Demartini B, Tundo A, Necci R, De Berardis D, Galentino R, De Michele S, Albert U, Rigardetto S, Maina G, Grassi G, Pallanti S, Amerio A, Amore M, Priori A, Servello D, Viganò C, Bosi M, Colombo A, Porta M, Dell’Osso B. Suicidal ideation and suicidal attempts in patients with obsessive-compulsive tic-related disorder vs obsessive-compulsive disorder: results of a multicenter Italian
study. CNS Spectr. 2020 May 6:1-8.
Pozza A, Veale D, Marazziti D, Delgadillo J, Albert U, Grassi G, Prestia D, Dèttore D. Sexual dysfunction and satisfaction in obsessive compulsive disorder: protocol for a systematic review and meta-analysis. Syst Rev. 2020 Jan 9;9(1):8.
Pozza A, Veale D, Marazziti D, Delgadillo J, Albert U, Grassi G, Prestia D, Dèttore D. Sexual dysfunction and satisfaction in obsessive compulsive disorder: protocol for a systematic review and meta-analysis. Syst Rev. 2020 Jan 9;9(1):8.
Dell’Osso B, Vismara M, Benatti B, Cirnigliaro G, Grancini B, Fineberg NA, Van Ameringen M, Hollander E, Stein DJ, Menchon JM, Rodriguez CI, Nicolini H, Lanzagorta N, Pallanti S, Grassi G, Lochner C, Marazziti D, Hranov G, Karamustafalioglu O, Hranov L, Zohar J. Lifetime bipolar disorder comorbidity and related clinical characteristics in patients with primary obsessive compulsive disorder:a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). CNS Spectr. 2019 May 27:1-7.
Grassi G, Makris N, Pallanti S. Addicted to compulsion: assessing three core dimensions of addiction across obsessive-compulsive disorder and gambling disorder. CNS Spectr. 2019 May
20:1-10.
Salerno L, Ramat S, Solari G, Grassi G, Pallanti S, Parkinson’s Disease with Impulse Control Disorders: Higher Prevalence (Frequency) of Symptoms of Attention Deficit Hyperactivity Disorder. International Journal of Clinical Psychiatry 2019, 7(1): 1-7
Fineberg NA, Dell’Osso B, Albert U, Maina G, Geller D, Carmi L, Sireau N, Walitza S, Grassi G, Pallanti S, Hollander E, Brakoulias V, Menchon JM, Marazziti D, Ioannidis K, Apergis-Schoute A, Stein DJ, Cath DC, Veltman DJ, Van Ameringen M, Fontenelle LF, Shavitt RG, Costa D, Diniz JB, Zohar J. Early intervention for obsessive compulsive disorder: An expert consensus statement. Eur Neuropsychopharmacol. 2019 Apr;29(4):549-565.
Grassi G, Pallanti S. Current and up-and-coming pharmacotherapy for obsessive-compulsive disorder in adults. Expert Opin Pharmacother. 2018 Oct;19(14):1541-1550.
Grassi G, Figee M, Ooms P, Righi L, Nakamae T, Pallanti S, Schuurman R, Denys D. Impulsivity and decision-making in obsessive-compulsive disorder after effective deep brain stimulation or treatment as usual. CNS Spectr. 2018 Oct;23(5):333-339.
Grassi G, Micheli L, Di Cesare Mannelli L, Compagno E, Righi L, Ghelardini C, Pallanti S. Atomoxetine for hoarding disorder: A pre-clinical and clinical investigation. Journal of Psychiatry
Research 2016 (83): 240-248.
Grassi G, Figee M, Stratta P, Rossi A, Pallanti S. Cognitive impulsivity and the behavioral addiction model of obsessive-compulsive disorder. J Behav Addict. 2016 Sep 28:1-3.
Grassi G, Pallanti S, Righi L, Figee M, Mantione M, Denys D, Piccagliani D, Rossi A, Stratta P. Think twice: impulsivity and decision-making in obsessive compulsive disorder. J Behav Addict. 2015 Dec; 4(4):263-72.
Grassi G, Godini L, Grippo A, Piccagliani D, Pallanti S. Enhancing cognitive-behavioral therapy with repetitive transcranial magnetic stimulation in refractory obsessive-compulsive disorder: a case report. BrainStimul. 2015 Jan-Feb;8(1):160-1
Pallanti S, Grassi G. Pharmacologic treatment of obsessive-compulsive disorder comorbidity. Expert Opin Pharmacother. 2014 Dec; 15(17): 2543-52.
Pallanti S, Grassi G, Cantisani A. Emerging drugs to treatobsessive-compulsive disorder. Expert Opin Emerg Drugs. 2014 Mar;19(1):67-77.
Pallanti S, Grassi G, Antonini S, Quercioli L, Salvadori E, Hollander E. rTMSin resistant mixed states: an exploratory study. J Affect Disord.,157:66-71;2014.
Grassi G, Poli L, Cantisani A, Righi L, Ferrari G, Pallanti S. Hypochondriasis and obsessivecompulsivedisorder in schizophrenic patients treated with clozapine vs other
atypicalantipsychotics. CNS Spectrum, 2014;19(4):340-6.
Grassi G, Pallanti S. Citalopram Pulse-Loading forSevere Treatment-Resistant OCD: A Case Series of Acute Response, One YearFollow-Up and Tolerability. J Depress Anxiety, 2013.
Pallanti S, Grassi G, Tofani L, Spitoni S. Pharmacologicaltreatments for behavioral addictions: from behavioral dimensions to theResearch Domain Criteria based target. Current
Psychopharmacology. 2013.
Pallanti S, Grassi G, Ramella-Cravaro V. From psychopatology toneurocircuits: what we can learn from DBS? The case of obsessive-compulsivedisorder. Journal of Psychopathology. 2013, in press Pallanti S, Cantisani A, Grassi G. Anxiety as a core aspect of schizophrenia. Curr Psychiatry Rep.2013, 15(5):354.
Pallanti S, Grassi G, Cantisani A. Is hoarding aseparate disorder? Neuropsychiatry, 2012, 2(5): 365-367.
Pallanti S, Cantisani A, Grassi G, Antonini S, Cecchelli C,Burian J, Cauli G, Quercioli L. rTMS age dependent response in treatment-resistant depressed subjects: a mini-review. CNS Spectr. 2012, 17(1):24-30.
Pallanti S, Grassi G, Burian J. Dopamine Pharmacological Agents in Resistant-OCD.Current Psychopharmacology, 2012, 1: 44-46
Pallanti S, Grassi G, Sarrecchia ED, Cantisani A, Pellegrini M.Obsessive-compulsive disorder comorbidity: clinical assessment and therapeuticimplications. Front Psychiatry. 2011, 2:70.
Cecchelli C, Grassi G, Pallanti S. Aripiprazole Improves Depressive Symptoms andImmunological Response to Antiretroviral Therapy in an HIV-Infected Subject with Resistant Depression. Case Report Med. 2010.
Capitoli su libri internazionali:
Salerno L, Gaur S, Grassi G, Pallanti S. (2020) Neuromodulation in Attention-Deficit/Hyperactivity Disorder: Toward a Precision Psychiatry Approach. In: Dell’Osso B., Di Lorenzo G. (eds) Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences. Springer, Cham.
Pallanti S, Grassi G, Cantisani A. Approaches to treatment resistance. Obsessive Compulsive Disorder: Current Science andClinical Practice. World Psychiatry Association. Wiley-Blackwell (Ed.). 2012
Pallanti S, Grassi G, Cantisani A. The Treatment of Obsessive-CompulsiveDisorder and the Approaches to Treatment Resistance, Different Views of AnxietyDisorders, Salih Selek (Ed.), ISBN: 978-953-307-560-0, InTech